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FANCD2重组兔单抗

简要描述:Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.

  • 产品型号:bsm-61302R
  • 厂商性质:生产厂家
  • 更新时间:2025-02-28
  • 访  问  量: 69

详细介绍

Human
WB,ICC/IF,IP
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

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